Category Archive : Technical Support

Potassium Humate application

Humic acids induced changes of the microbiome

The mean microbial concentration after 45 d of supplementation of humic acids increased 14% in the essential groups (P < 0.01), 28% (NS) in the individual pioneer groups and 41% (P < 0.002) in the individual substantial groups. The accidental bacterial groups with initially marginal concentrations demonstrated no response to humic acids.

The response to humic acids of single bacterial groups was principally the same as in all functional sets of substantial bacteria. The concentrations of most bacterial groups within essential (2 of 3) pioneer (3 of 4) and individual substantial groups (19 of 28) increased in rates of 20% to 60%. In most cases, the increase was observed already at day 10 and continued to day 45. In groups with comparatively low initial mean concentrations (Ebac1790, Cdif198, Chis150, Eram997, Lab158, Veil223) an increase could be higher than 70% and up to 96%, but the contribution of these groups to the overall bacterial numbers was relatively low. Only the concentrations of bacteria detected with Bac303 (Bacteroides) and Myc657 (mycolic acid-containing Actinomycetes) FISH probes decreased under humic acids supplementation, but was statistically not significant, because of the high variance and low number of probands.

The increase in concentrations of microbiota was caused by preexisting groups, and not due to emerging new microorganisms. The individual microbial profile remained constant. In none of the test persons did the ratio of positive/negative individual groups change more than 5%.

Humic acid supplementation did not affect microbial diversity. Mean percent of substantial individual bacterial groups positive for bacteria for each person was nearly the same over time with 72%; 74%; 76%; 72% at the control days accordingly.

The patterns in distribution of single bacterial groups over the stool cylinder differed depending on the species but remained the same in the mucus close transient zone and in the center of the fecal cylinder regardless of humic acids supplementation.

Humic Substance

Humic substances are complex organic substances of soil, which are formed in the process of humification. Humification involves natural chemical and microbial activity that transforms the dead remains of living things into humic substances.

It is the second greatest organic process on earth after photosynthesis and is responsible for fossil coal, oil deposits and others. Microorganisms utilize and break down organic substances and lead to accumulation of recalcitrant molecules. When microorganisms die, they are themselves broken down and added to the recalcitrant humic mass. The concurrent chemical-physical polymerization modifies humic substances in an unpredictable matter. In all, the genesis of humic substances can take hundreds or even thousands of years and leads to high variety, unique composition and extreme difficulties in characterization of these.

The growing interest of the modern society for environmental and biological welfare refreshed the attractiveness for implementation of humins. Gastroenterologists are often confronted with a wish of patients to be treated with “natural” products and asked for opinion on humic acids.

The study of the scientific literature reveals a large number of medical trials with dietary supplements of humic acids conducted all over the world. The reported effects include different, partially incoherent properties such as anti-inflammatory and immune-stimulatory as well as analgesic, antimicrobial, antiviral/anti-HIV activity, antioxidant and even stroke protective effects. The striking eclecticism of the findings and the lack of systematic studies make it difficult to build an unbiased opinion. Furthermore humic substances are distributed under a wide variety of trade names and descriptions in an unregulated market.

The colon is a central bio-fermenting organ degrading digestive leftovers. Since microbial activity is central in genesis and processing of humic acids, the innate human microbial communities should be the main object on which the effects of humic acids will be apparent.

Astonishingly, we found no data to this topic in the literature. In order to close this gap, we investigated the impact of orally applied Activomin® (Pharmawerk Weinboehla, Weinboehla, Germany) on concentrations and diversity of the human colonic microbiome. Activomin® is the only registered and standardized humic acids preparation in Germany.

Impact of humic acids on the colonic microbiome in healthy volunteers

The sum concentration of colonic microbiota increased from 20% at day 10 to 30% by day 31 and remained stable until day 45 (32%) of humic acid supplementation (P < 0.001). The increase in the concentrations in each person was due to growth of preexisting groups.

The individual microbial profile of the patients remained unchanged. Similarly, the bacterial diversity remained stable. Concentrations of 24 of the 35 substantial groups increased from 20% to 96%.

Two bacterial groups detected with Bac303 (Bacteroides) and Myc657 (mycolic acid-containing Actinomycetes) FISH probes decreased (P > 0.05). The others remained unaffected. Bacterial groups with initially marginal concentrations (< 0.1 × 109/mL) demonstrated no response to humic acids. The concentrations of pioneer groups of BifidobacteriaceaeEnterobacteriaceae and Clostridium difficile increased but the observed differences were statistically not significant.

Core tip: Modern patients are increasingly interested in natural medicinal products, which are often not scientifically evaluated. Humins arise from organic microbial degradation and are an important mediator of microbial interactions in nature.

Although used for medical indications since ancient times, no data exist on the impact of humins on the human microbiome. Our investigations in healthy volunteers show that orally applied humic acids increase the sum concentrations of preexisting colonic microbiota from 20% to 30% without changes in the bacterial diversity of the individual microbiome and may be a serious amendment/alternative to fecal transplantation or probiotics.

All great ancient cultures were based on agriculture for which soil quality and prevention of its exhaustion were absolutely critical. Humus as an organic fecundity substrate of the earth excited thinkers from the ancient times and stimulated both solid research and charlatanry.

First descriptions of medical applications can be found in Sanskrit and also ancient writings of Rome and China. Despite nearly mystic reverence and enormous interest, it is not before the early 1800s that chemical characterization and description of humic acids took place.

Potassium humate benefits farming

Potassium humate is important in agricultural production

Potassium humate is important in agricultural production ,due to Potassium humate is a high-efficiency organic potassium fertilizer, because humic acid is a biologically active preparation, which can increase soil available potassium content, reduce potassium loss and fixation, increase crop potassium absorption and utilization, and improve Soil, promote crop growth, improve crop resilience, improve crop quality, and protect agricultural ecosystems. With the deepening of the concept of balanced fertilization, the source of humic acid has been accepted by more and more people, and is expected to be high. This article will introduce the effect of potassium humate.

Potassium humate is the best “companion” for improving quality and enhancing fertilizers. In recent years, the National Agricultural Technology Extension Service Center has carried out “two highs and three lesss”, “three doses” and “three effects” in the demonstration of Potassium humate fertilizer. “The new results have fully proved the superior effect of potassium humate to enhance the efficiency of chemical fertilizers.

Potassium humate regulates soil acid and alkalinity – potassium humate has a molecular weight ranging from several hundred to millions, and contains a variety of reactive functional groups. It can be developed through a variety of processes to adapt to alkaline or acidic soils. product.

Potassium humate meets the requirements of agricultural production – potassium humate can be adapted to local conditions, meet the needs of soil production under different time and space, zone and natural environment conditions, and meet the current agricultural production status and requirements.

Potassium humate rapidly increases soil fertility – the soil organic matter is less than two or three years old, and more than one hundred years. Industrial development using potassium humate can shorten the time of decomposing organic matter, benefiting it in the current year and even benefiting in the current season.
The combination of organic and inorganic humic acid potassium is good. Potassium humate can be combined with large, medium and micro nutrients and beneficial elements. Once combined, the best state of matching can be achieved. In the case of equal nutrients, potassium humate increased by an average of 10 percentage points or more, equivalent to a net increase of 30% to 40%.

Potassium humate can repair heavy metal pollution in soil – potassium humate can not only reduce the content of heavy metal pollutants in the soil, but also improve the “self-repairing” function of the soil, which is an excellent choice for soil remediation.

Potassium humate is a climatic factor of indigenous soils. Soil humic acid potassium itself has low carbonization properties. It uses humic acid potassium fertilizer and its derivatives to feed agriculture, save energy, low carbon, reduce emissions, and increase green color. It is more effective in developing climate agriculture. .

Four advantages of Beijing carbon source power high activity humic acid potassium
First, the use of modern technology to purify the mineral source of water-soluble humic acid potassium, provides a favorable guarantee for the production of green health food, reduce environmental pollution, reduce farmers’ production costs.

Second, it can greatly increase nitrogen, dissolve phosphorus, and promote potassium in the soil, cultivate soil fertility, and promote crop root development.

Third, it can be widely applied to food crops, cash crops, oil crops and flowers, etc. It has a wide range of crops and a wide range of use concentrations.

Fourth, the combination of potassium humate and nutrients is reasonable and has a synergistic nutritional effect, which can greatly reduce the use of chemical fertilizers and pesticides.

Potassium humate is the most active element of organic matter in soil. The role of potassium humate can be summarized as “five doses”: soil improvers, fertilizer synergists, good pesticides, and antidote to pollutants. , a promoter of plant growth.

humic acid function

Potassium humate for Cr(VI) removal

Potassium humate possesses a wide variety of oxygen-containing functional groups and has good adsorption and complexion properties for many kinds of transition metal ions.

In this work, a simple and separable route had been developed to synthesize Fe3O4/graphene nanocomposite, derived from potassium humate, were employed for the effective adsorption of Cr(VI) in aqueous phase. In addition, the Fe3O4/graphene nanocomposite prepared at 600 °C (S-600) showed a maximum adsorption capacity of 280.6 mg/g for Cr(VI) and good cycling performance, which was much higher than those reported graphene-based adsorbents and other conventional adsorbents.

The adsorptive behavior was well fitted to the Langmuir isotherm model. The adsorption kinetics for removal of Cr(VI) agreed with pseudo-second-order equation, which indicates a kind of chemical adsorption. Its superior adsorption performance might be due to the effective adsorption sites at the surface and formation of FeOH2+ on the surface of Fe3O4/graphene. This work provided a promising approach for the removal of Cr(VI) from wastewater using a Fe3O4/graphene nanocomposite, which shows a huge number of application prospects.