Overview of the pharmacological effects of sodium humate
- Activated absorption of feed ingredients
Due to the large molecular weight of humic acid itself, larger particles can be formed in a certain medium, so it has colloidal properties and adsorption capacity, forming good ion exchange and catalysis, and promoting the activation and absorption of feed components.
1.1 Sodium humate fully decomposes various complex molecular nutrients in the feed and performs good organic combination, increases gastrointestinal function, and promotes protein assimilation.
1.2 Sodium humate enhances the permeability of animal cell membranes and protoplasts, and increases the amount of interstitial water and cell water content in muscle cells, and causes the phenomenon of bristles in pigs.
1.3 The adsorption of humic acid makes the feed nutrient slower through the intestine, enhances the absorption and digestion time, and improves the absorption rate of nutrients.
1.4 The humic acid molecule is rich in nitrogen and has a strong absorption of amino groups. It makes the non-protein amide in the feed fully utilized, and the feed protein is converted to muscle protein at a higher level, and the lean growth potential is exerted. To increase the proportion of lean meat, while the humic acid molecules remaining in the intestine can also absorb the ammonia in the feces, which not only reduces the odor of the feces, but also increases the fertilizer efficiency by absorbing ammonia.
1.5 The sulfhydryl group contained in humic acid participates in the redox process of the body, which makes the metabolism strong, promotes cell proliferation and accelerates growth.
1.6 Sodium humate can improve gastrointestinal function, promote gastric secretion, increase appetite, promote nutrients into the body faster, stimulate the growth of beneficial bacteria in the gastrointestinal tract, and inhibit the proliferation of spoilage bacteria.
1.7 Since sodium humate can promote digestion and absorption, it can better absorb and utilize the mineral elements in the feed compatibility, and fully exert the functions of mineral elements and multivitamins.
2 effects on endocrine function
2.1 Humic acid can stimulate the secretion of certain glands, inhibit sympathetic nerves, cause drowsiness, increase the time of the carcass in sleep or quiet state, and generally reduce the body movement and visceral activity. This aspect is beneficial to the assimilation of the whole body. In order to restore the organ system in time, the body temperature of the livestock is reduced, the heat consumption and excess exercise energy are reduced, and the storage energy is relatively increased, thereby increasing the deposition of muscle and fat and improving the feed conversion. rate.
2.2 Humic acid can activate the function of the pituitary-adrenal cortex, promote the secretion of ACTH, increase the secretion of estrogen, and stimulate the balance of the thyroid.
3 antibacterial anti-inflammatory effect
3.1 Humic acid can promote the release of corticosteroids and ACTH by inhibiting the release of corticosteroids and ACTH, inhibiting the synthesis of prostate E (prostaglandins are carriers of pain processes), and can increase the capillary permeability caused by amines.
3.2 Sodium humate is a polymer complex and contains alkaloids, so it has strong adsorption capacity for intestinal inflammatory substances and toxic substances, and has astringent effect on intestinal mucosa. In addition, due to the structure of sodium humate A variety of active groups, which can shrink blood vessels, reduce capillary permeability, and play an anti-inflammatory and hemostatic effect.
3.3 Under the action of various enzymes, the active group in the sodium humate molecule can decompose more nascent oxygen and exhibit bactericidal action.
4 antiviral effect
4.1 Humic acid is different from antibiotics in that it is not decomposed by mold and bacteria, and at the same time denatures viral proteins, thereby producing an antiviral effect.
4.2 Sodium humate can prevent DNA viruses (naked and entrapped) from being attached to cells and unable to multiply. In addition, it inhibits reverse transcriptase activity and inhibits virus synthesis.
5 promote wound healing
5.1 Sodium humate has a good antiseptic effect on soft wounded suppurative infection. Infected body cells, under the stimulation and damage of microorganisms, local cells lack oxygen to cause necrosis, and isolate harmful ions and poisons. The product destroys health and expands the wound. After contact with the wound surface, sodium humate eliminates metal ions and poisons due to changes in physical and chemical properties, and the odor and secretion of pus are also reduced.
5.2 Sodium humate can quickly form a protective film on the wound surface and shrink the tiny blood vessels to stop bleeding. Because the molecular structure of sodium humate determines that it is both an oxidant and a reducing agent, it can separate nascent oxygen from the second, increase the internal respiration of cells, promote cell metabolism, and facilitate the survival of inter-ecological cells and the production of granulation. The infection is effectively controlled.
5.3 Sodium humate can increase the number of platelets, shrink blood vessels, reduce capillary permeability, and reverse abnormal microcirculation perfusion to promote normal recovery.
5.4 Sodium humate can stimulate the synthesis of prostaglandins in the gastric mucosa, increase the blood flow of the gastric mucosa, protect the gastric mucosa, and heal the ulcer.
6 effects on immune function
6.1 Sodium humate can increase the spleen weight of mice and rabbits, enlarge the white pulp area, increase the number of red pulp cells, and produce large macrophages, thereby enhancing the function of immune organs.
6.2 Sodium humate has an excitatory effect on the function of the reticuloendothelial system, ie on non-specific immune function.
6.3 Sodium humate has the effect of enhancing humoral immune function.
6.4 Sodium humate can increase the leaching rate, has the effect of phytohemagglutinin (PHA), and participate in cellular immunity.
- Toxicology and detoxification of sodium humate
Sodium humate has been proved to be safe and non-toxic by general toxicity and special toxicity tests. For example, sodium humate is administered orally to rats with LD50? 12g/kg, and humic acid is used to administer LD50? 3150mg/kg in mice. The amount of LD50? 4 g / kg. Sodium humate is not only non-toxic but also detoxifying. It has detoxification effects on heavy metals and strychnine, and can reduce urea toxicity.